Group Members

Miranda Brun
Devon Germain
Darryl Glubrecht
Saket Jain
David Jay
Lei Li
Rong-Zong Liu
Elizabeth Monckton
Kevin Vo
Jack Wang
Xia Xu

Darryl Glubrecht, B.Sc.,  Research Technologist


B.Sc. Chemistry, Biological Sciences Minor, University of Alberta

Techniques: immunohistochemistry, immunofluorescence, western blot analysis, in situ hybridization, affinity purification, preparation of recombinant protein


Publications:

Spratlin J, Sangha R, Glubrecht D, Dabbagh L, Young JD, Dumontet C, Cass C, Lai R, Mackey JR. The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma. Clin. Cancer Res. 10: 6956-6961 (2004).

Mackey JR, Galmarini CM, Graham KA, Joy AA, Delmer A, Dabbagh L, Glubrecht D, Jewell LD, Lai R, Lang T, Hanson J, Young JD, Merle-Béral H, Binet JL, Cass CE, Dumontet C. Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): identification of fludarabine-sensitive and -insensitive populations. Blood 105: 767-774 (2005)
Katyal, S.1, Gao, Z.1, Monckton, E.A., Glubrecht, D.D. and Godbout, R. The hierarchical nature of Dab1 tyrosine phosphorylation specifies Src-family kinase activation and neuritogenesis. J. Mol. Biol. 368: 349-364 (2007). 1co-first authors

Mita, R. Coles, J.E., Glubrecht, D., Sung, R. Sun, X. and Godbout, R. B-FABP-expressing radial glial cells – the malignant glioma cell-of-origin? Neoplasia 9: 734-744 (2007).

Li. X., Glubrecht, D.D., Mita, R. and Godbout, R. Expression of AP-2d in the developing chick retina. Dev. Dyn. 237: 3210-3221 (2008).

Brun, M.1, Coles, J.E.1, Monckton, E.A., Glubrecht, D.D., Bisgrove, D.A. and Godbout, R. Nuclear Factor I Regulates Brain Fatty Acid-binding Protein and Glial Fibrillary Acidic Protein Gene Expression in Malignant Glioma Cell Lines.  J. Mol. Biol. 391: 282-300 (2009). 1co-first authors

Glubrecht, D.D., Kim, J.-H., Russell, L. Bamforth, J.S. and Godbout, R. Differential CRX and OTX2 Expression in Human Retina and Retinoblastoma. J. Neurochem. 111: 250-263 (2009). *Figure from manuscript featured on cover of J. Neurochem. Vol. 112, Issue 2 (2010).

Li. X., Glubrecht, D.D. and Godbout, R. The AP-2 transcription factor induces apoptosis in retinoblastoma cells. Genes Chromosomes Cancer 49: 819-830 (2010).

Germain, D.R., Graham, K., Glubrecht, D.D., Hugh, J.C., Mackey, J.R. and Godbout, R. DEAD Box 1: A Novel and Independent Prognostic Marker for Early Recurrence in Breast Cancer. Breast Cancer Res. Treat. (in press).

Gao, Z., Monckton, E.A., Glubrecht, D.D. and Godbout, R. Early Isoform of Disabled-1 Functions Independently of Reelin-mediated Tyrosine Phosphorylation in Chick Retina. Mol. Cell. Biol. 30: 4339-4353 (2010).

Liu, R.-Z., Graham, K., Glubrecht, D.D., Mackey, J.R. and Godbout, R. Association of FABP5 expression with poor survival in triple-negative breast cancer: implication for retinoic acid therapy. Am. J. Pathol. (in press).